Genetically transformed Listeria monocytogens are tried to used as a vaccine for HIV.
Recombinant L. monocytogenes bacteria have been successfully used as biologic vaccine vectors against lymphocytic choriomeningitis virus, cottontail rabbit papillomavirus, murine influenza, and murine neoplasms. Several studies using the mouse model have demonstrated the potential of L. monocytogenes as an HIV vaccine vector.
Recombinant L. monocytogenes can induce a strong CTL response and long-lived memory response to HIV Gag and that oral administration with recombinant L. monocytogenes stimulates a strong intestinal mucosal cellular immune response.
Recombinant L. monocytogenes bacteria have been successfully used as biologic vaccine vectors against lymphocytic choriomeningitis virus, cottontail rabbit papillomavirus, murine influenza, and murine neoplasms. Several studies using the mouse model have demonstrated the potential of L. monocytogenes as an HIV vaccine vector.
Recombinant L. monocytogenes can induce a strong CTL response and long-lived memory response to HIV Gag and that oral administration with recombinant L. monocytogenes stimulates a strong intestinal mucosal cellular immune response.
Posts
No comments:
Post a Comment